Atmospheric Control Module

Safe, Automatic, & Pressurized Containment for HPAPIs

ILC Dover’s Atmospheric Control Module (ACM) provides risk mitigation and automatic processing control for higher-potency active pharmaceutical ingredients (HPAPIs) within laboratories and GMP manufacturing operations.

The ACM is designed for use with ILC Dover’s ArmorFlex® Flexible Isolator. Its precise fan speed and pressure gas regulation facilitates negative pressure operation within flexible-wall isolators. The module works with air or nitrogen, and features a portable and compact design, fully automated vacuum control and breach response, and superior ergonomics for operators.

Portable and Compact
Can be connected to existing and new flexible isolators. Frames can be retrofitted to accommodate the push-push HEPA filter. The enclosure is modified for the gas supply, exhaust, and differential pressure sensor connections.

Fully Automated Control
Allows for easy and confident contained handling of expensive and dangerous powders. Detects any pressure change, immediately adjusting the internal isolator pressure back to the set point to ensure continual risk mitigation.

Vacuum Control and Breach Response
Units can attain and maintain a set point of -15 Pa using controlled pressure gas feed and extract fan speed, so enclosures remain ergonomic and easy to work with.

Works with Air or Nitrogen
Can be used with N2 for materials that are oxygen sensitive or explosive. It can use fresh or recirculated N2 and can reduce humidity with an appropriate gas supply.

Range of Motion for Operators
Flexible isolators provide the optimum ergonomic operation by use of a flexible film and stainless-steel frame that is supported by stretch cords which allow a generous range of motion. It does not restrict operator movement unlike hard-wall isolators or a laminar flow hood with a sash.

The ACM’s fully automated provision of negative air pressure provides additional risk mitigation when operating flexible-wall isolators, further reducing the risk of operator exposure. It can be operated to maintain positive air pressure within the flexible isolator for applications requiring sterility, as well as facilitate relative-humidity control. The module is available in single-fan and dual-fan configurations. The single-fan system satisfies most applications.