Single-use powder transfer bags can be removed, discarded and replaced when a manufacturing process is finished.
One word frequently surfaces during discussions on pharmaceutical manufacturing. That word? Containment. Because confining the toxic substances involved in the manufacturing process— like powder, dust and vapors—is a necessity for safety. And even microscopic amounts of those materials that escape into the air can harm workers and contaminate life-saving medications.
Containment lapses can result in manufacturing plant closures and huge losses. In 2009, one manufacturing plant closed after a virus contaminated a bioreactor. And the shutdown halted production of two medications that were used by 8,000 patients globally. The company lost $300 million in sales.
After six months, manufacturer began producing the medications again, but both drugs were still in short supply more than one year later.